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Blood biomarkers as surrogate endpoints of treatment responses to aerobic exercise and cognitive training (ACT) in amnestic mild cognitive impairment: the blood biomarkers study protocol of a randomized controlled trial (the ACT Trial)

BACKGROUND: Alzheimer’s disease (AD) is an epidemic with tremendous public health impacts because there are currently no disease-modifying therapeutics. Randomized controlled trials (RCTs) for prevention of AD dementia often use clinical endpoints that take years to manifest (e.g., cognition) or sur...

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Detalles Bibliográficos
Autores principales: Li, Danni, Mielke, Michelle M., Bell, W. Robert, Reilly, Cavan, Zhang, Lin, Lin, Feng Vankee, Yu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943901/
https://www.ncbi.nlm.nih.gov/pubmed/31907024
http://dx.doi.org/10.1186/s13063-019-3798-1