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Naringin Protects Against Interleukin 1β (IL-1β)-Induced Human Nucleus Pulposus Cells Degeneration via Downregulation Nuclear Factor kappa B (NF-κB) Pathway and p53 Expression

BACKGROUND: Low back pain (LBP) is regarded as a frequent disease that causes disability. We aimed to explore the effect of naringin on intervertebral disc degeneration (IDD) in IL-1β-induced human nucleus pulposus (NP) cells and its corresponding molecular mechanisms. MATERIAL/METHODS: Human NP cel...

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Detalles Bibliográficos
Autores principales: Gao, Gang, Chang, Feng, Zhang, Ting, Huang, Xinhu, Yu, Chen, Hu, Zhaolin, Ji, Mingming, Duan, Yufen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944037/
https://www.ncbi.nlm.nih.gov/pubmed/31927560
http://dx.doi.org/10.12659/MSM.918597