High-quality draft genome and characterization of commercially potent probiotic Lactobacillus strains

Lactobacillus acidophilus UBLA-34, L. paracasei UBLPC-35, L. plantarum UBLP-40, and L. reuteri UBLRU-87 were isolated from different varieties of fermented foods. To determine the probiotic safety at the strain level, the whole genome of the respective strains was sequenced, assembled, and character...

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Detalles Bibliográficos
Autores principales: Sulthana, Ayesha, Lakshmi, Suvarna G., Madempudi, Ratna Sudha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2019
Materias:
Genomic Archive
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944049/
https://www.ncbi.nlm.nih.gov/pubmed/31896243
http://dx.doi.org/10.5808/GI.2019.17.4.e43
Descripción
Sumario:Lactobacillus acidophilus UBLA-34, L. paracasei UBLPC-35, L. plantarum UBLP-40, and L. reuteri UBLRU-87 were isolated from different varieties of fermented foods. To determine the probiotic safety at the strain level, the whole genome of the respective strains was sequenced, assembled, and characterized. Both the core-genome and pan-genome phylogeny showed that L. reuteri was closest to L. plantarum than to L. acidophilus, which was closest to L. paracasei. The genomic analysis of all the strains confirmed the absence of genes encoding putative virulence factors, antibiotic resistance, and the plasmids.

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