Defective postreplication repair of UV photoproducts in melanoma: a mutator phenotype

In this issue, the Gabrielli laboratory and collaborators address the bulky CPD lesions created in DNA when UV joins two adjacent pyrimidines (thymine or cytosine), leading to skin cancers such as melanoma (Pavey S et al. (2019) Mol Oncol). Our understanding of postreplication repair mechanisms for...

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Detalles Bibliográficos
Autores principales: Brash, Douglas E., Seidman, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944110/
https://www.ncbi.nlm.nih.gov/pubmed/31821728
http://dx.doi.org/10.1002/1878-0261.12612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944110/
https://www.ncbi.nlm.nih.gov/pubmed/31821728
http://dx.doi.org/10.1002/1878-0261.12612

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