Cargando…

Defective postreplication repair of UV photoproducts in melanoma: a mutator phenotype

In this issue, the Gabrielli laboratory and collaborators address the bulky CPD lesions created in DNA when UV joins two adjacent pyrimidines (thymine or cytosine), leading to skin cancers such as melanoma (Pavey S et al. (2019) Mol Oncol). Our understanding of postreplication repair mechanisms for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brash, Douglas E., Seidman, Michael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944110/ https://www.ncbi.nlm.nih.gov/pubmed/31821728 http://dx.doi.org/10.1002/1878-0261.12612

Ejemplares similares

Multiple interaction nodes define the postreplication repair response to UV‐induced DNA damage that is defective in melanomas and correlated with UV signature mutation load
por: Pavey, Sandra, et al.
Publicado: (2019)

Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing
por: Becker, Jordan R., et al.
Publicado: (2015)

Atypical UV Photoproducts Induce Non-canonical Mutation Classes Associated with Driver Mutations in Melanoma
por: Laughery, Marian F., et al.
Publicado: (2020)

The Rate and Spectrum of Spontaneous Mutations in Mycobacterium smegmatis, a Bacterium Naturally Devoid of the Postreplicative Mismatch Repair Pathway
por: Kucukyildirim, Sibel, et al.
Publicado: (2016)

RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA
por: Lazzaro, Federico, et al.
Publicado: (2012)

A Majority of Human Melanoma Cell Lines Exhibits an S Phase-Specific Defect in Excision of UV-Induced DNA Photoproducts
por: Bélanger, François, et al.
Publicado: (2014)

Dynamics and Mechanism of Repair of UV-induced (6-4) Photoproduct by Photolyase
por: Li, Jiang, et al.
Publicado: (2010)

Human Telomeres Are Hypersensitive to UV-Induced DNA Damage and Refractory to Repair
por: Rochette, Patrick J., et al.
Publicado: (2010)

Requirement of Replication Checkpoint Protein Kinases Mec1/Rad53 for Postreplication Repair in Yeast
por: Gangavarapu, Venkateswarlu, et al.
Publicado: (2011)

The Mre11-Rad50-Xrs2 Complex Is Required for Yeast DNA Postreplication Repair
por: Ball, Lindsay G., et al.
Publicado: (2014)

Human HLTF mediates postreplication repair by its HIRAN domain-dependent replication fork remodelling
por: Achar, Yathish Jagadheesh, et al.
Publicado: (2015)

Anc1, a Protein Associated with Multiple Transcription Complexes, Is Involved in Postreplication Repair Pathway in S. cerevisiae
por: Erlich, Rachel L., et al.
Publicado: (2008)

Rad51 Accumulation at Sites of DNA Damage and in Postreplicative Chromatin
por: Tashiro, Satoshi, et al.
Publicado: (2000)

Monitoring Repair of UV-Induced 6-4-Photoproducts with a Purified DDB2 Protein Complex
por: Dreze, Matija, et al.
Publicado: (2014)

The MCM-Binding Protein ETG1 Aids Sister Chromatid Cohesion Required for Postreplicative Homologous Recombination Repair
por: Takahashi, Naoki, et al.
Publicado: (2010)

Transcription and DNA repair collide after UV exposure
por: Adeyemi, Richard O.
Publicado: (2023)

Sulfolobus Mutants, Generated via PCR Products, Which Lack Putative Enzymes of UV Photoproduct Repair
por: Sakofsky, Cynthia J., et al.
Publicado: (2011)

Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme
por: Benjdia, Alhosna, et al.
Publicado: (2012)

Mapping atypical UV photoproducts in vitro and across the S. cerevisiae genome
por: Bohm, Kaitlynne A., et al.
Publicado: (2021)

Generation of supercoils in nicked and gapped DNA drives DNA unknotting and postreplicative decatenation
por: Racko, Dusan, et al.
Publicado: (2015)

Yeast Rad5 Protein Required for Postreplication Repair Has a DNA Helicase Activity Specific for Replication Fork Regression
por: Blastyák, András, et al.
Publicado: (2007)

The amino-terminal tails of histones H2A and H3 coordinate efficient base excision repair, DNA damage signaling and postreplication repair in Saccharomyces cerevisiae
por: Meas, Rithy, et al.
Publicado: (2015)

Topoisomerase II deficiency leads to a postreplicative structural shift in all Saccharomyces cerevisiae chromosomes
por: Ayra-Plasencia, Jessel, et al.
Publicado: (2021)

Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation
por: Schermelleh, Lothar, et al.
Publicado: (2007)

PrimPol Bypasses UV Photoproducts during Eukaryotic Chromosomal DNA Replication
por: Bianchi, Julie, et al.
Publicado: (2013)

UV-visible photodegradation of naproxen in water – Structural elucidation of photoproducts and potential toxicity
por: Cazzaniga, Noemi, et al.
Publicado: (2020)

Damage mapping techniques and the light they have shed on canonical and atypical UV photoproducts
por: Bohm, Kaitlynne A., et al.
Publicado: (2023)

Frequent template switching in postreplication gaps: suppression of deleterious consequences by the Escherichia coli Uup and RadD proteins
por: Romero, Zachary J, et al.
Publicado: (2020)

The role of BRAF V600 mutation in melanoma
por: Ascierto, Paolo A, et al.
Publicado: (2012)

RecF protein targeting to postreplication (daughter strand) gaps I: DNA binding by RecF and RecFR
por: Henry, Camille, et al.
Publicado: (2023)

Commentary: Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure
por: Gajula, Rajendra P., et al.
Publicado: (2015)

Structural basis of pyrimidine-pyrimidone (6–4) photoproduct recognition by UV-DDB in the nucleosome
por: Osakabe, Akihisa, et al.
Publicado: (2015)

Contributions of replicative and translesion DNA polymerases to mutagenic bypass of canonical and atypical UV photoproducts
por: Vandenberg, Brittany N., et al.
Publicado: (2023)

Photoproduction
por: Rollnik, H
Publicado: (1965)

Hereditary Disorders with Defective Repair of UV-Induced DNA Damage
por: Moriwaki, Shinichi
Publicado: (2013)

Accelerating cancer without mutations
por: Brash, Douglas E
Publicado: (2019)

Introduction to Photoproduction
por: Lohrmann, E
Publicado: (1969)

Structure Determination of Felodipine Photoproducts in UV-Irradiated Medicines Using ESI-LC/MS/MS
por: Kawabata, Kohei, et al.
Publicado: (2023)

Cellular Dynamics of Rad51 and Rad54 in Response to Postreplicative Stress and DNA Damage in HeLa Cells
por: Choi, Eui-Hwan, et al.
Publicado: (2017)

New Mechanisms of DNA Repair Defects in Fused in Sarcoma–Associated Neurodegeneration: Stage Set for DNA Repair-Based Therapeutics?
por: Wang, Haibo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0rd6vflqcpd52cvdesep7u1nhs