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Individual and joint performance of DNA methylation profiles, genetic risk score and environmental risk scores for predicting breast cancer risk

DNA methylation patterns in the blood, genetic risk scores (GRSs), and environmental risk factors can potentially improve breast cancer (BC) risk prediction. We assessed the individual and joint predictive performance of methylation, GRS, and environmental risk factors for BC incidence in a prospect...

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Detalles Bibliográficos
Autores principales: Guan, Zhong, Raut, Janhavi R., Weigl, Korbinian, Schöttker, Ben, Holleczek, Bernd, Zhang, Yan, Brenner, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944111/
https://www.ncbi.nlm.nih.gov/pubmed/31677238
http://dx.doi.org/10.1002/1878-0261.12594