Regulation of the MDM2‐p53 pathway by the ubiquitin ligase HERC2

The p53 tumor suppressor protein is a transcription factor that plays a prominent role in protecting cells from malignant transformation. Protein levels of p53 and its transcriptional activity are tightly regulated by the ubiquitin E3 ligase MDM2, the gene expression of which is transcriptionally re...

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Detalles Bibliográficos
Autores principales: García‐Cano, Jesús, Sánchez‐Tena, Susana, Sala‐Gaston, Joan, Figueras, Agnès, Viñals, Francesc, Bartrons, Ramon, Ventura, Francesc, Rosa, Jose Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944118/
https://www.ncbi.nlm.nih.gov/pubmed/31665549
http://dx.doi.org/10.1002/1878-0261.12592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944118/
https://www.ncbi.nlm.nih.gov/pubmed/31665549
http://dx.doi.org/10.1002/1878-0261.12592

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