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A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity

Asthma is a chronic inflammatory disease of the airways with contributions from genes, environmental exposures, and their interactions. While genome-wide association studies (GWAS) in humans have identified ~200 susceptibility loci, the genetic factors that modulate risk of asthma through gene-envir...

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Detalles Bibliográficos
Autores principales: Maazi, Hadi, Hartiala, Jaana A., Suzuki, Yuzo, Crow, Amanda L., Shafiei Jahani, Pedram, Lam, Jonathan, Patel, Nisheel, Rigas, Diamanda, Han, Yi, Huang, Pin, Eskin, Eleazar, Lusis, Aldons. J., Gilliland, Frank D., Akbari, Omid, Allayee, Hooman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944376/
https://www.ncbi.nlm.nih.gov/pubmed/31869344
http://dx.doi.org/10.1371/journal.pgen.1008528