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A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity
Asthma is a chronic inflammatory disease of the airways with contributions from genes, environmental exposures, and their interactions. While genome-wide association studies (GWAS) in humans have identified ~200 susceptibility loci, the genetic factors that modulate risk of asthma through gene-envir...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944376/ https://www.ncbi.nlm.nih.gov/pubmed/31869344 http://dx.doi.org/10.1371/journal.pgen.1008528 |