Cargando…

A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity

Asthma is a chronic inflammatory disease of the airways with contributions from genes, environmental exposures, and their interactions. While genome-wide association studies (GWAS) in humans have identified ~200 susceptibility loci, the genetic factors that modulate risk of asthma through gene-envir...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maazi, Hadi, Hartiala, Jaana A., Suzuki, Yuzo, Crow, Amanda L., Shafiei Jahani, Pedram, Lam, Jonathan, Patel, Nisheel, Rigas, Diamanda, Han, Yi, Huang, Pin, Eskin, Eleazar, Lusis, Aldons. J., Gilliland, Frank D., Akbari, Omid, Allayee, Hooman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944376/ https://www.ncbi.nlm.nih.gov/pubmed/31869344 http://dx.doi.org/10.1371/journal.pgen.1008528

Ejemplares similares

Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma
por: Han, Yi, et al.
Publicado: (2020)

Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity
por: Galle-Treger, Lauriane, et al.
Publicado: (2016)

The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants
por: Crow, Amanda L., et al.
Publicado: (2015)

CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation
por: Shafiei-Jahani, Pedram, et al.
Publicado: (2021)

The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice
por: Zhou, Xiaoying, et al.
Publicado: (2015)

The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction
por: Lavinsky, Joel, et al.
Publicado: (2016)

TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity
por: Hurrell, Benjamin P., et al.
Publicado: (2019)

Orai inhibition modulates pulmonary ILC2 metabolism and alleviates airway hyperreactivity in murine and humanized models
por: Howard, Emily, et al.
Publicado: (2023)

Distinct Roles of LFA-1 and ICAM-1 on ILC2s Control Lung Infiltration, Effector Functions, and Development of Airway Hyperreactivity
por: Hurrell, Benjamin P., et al.
Publicado: (2020)

Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection
por: Hilser, James R., et al.
Publicado: (2021)

Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss
por: Lavinsky, Joel, et al.
Publicado: (2015)

Correction: Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss
por: Lavinsky, Joel, et al.
Publicado: (2015)

Ambient Air Pollution Is Associated With the Severity of Coronary Atherosclerosis and Incident Myocardial Infarction in Patients Undergoing Elective Cardiac Evaluation
por: Hartiala, Jaana, et al.
Publicado: (2016)

PD-1 pathway regulates ILC2 metabolism and PD-1 agonist treatment ameliorates airway hyperreactivity
por: Helou, Doumet Georges, et al.
Publicado: (2020)

Build your first Ethereum DApp
por: Škvorc, Bruno
Publicado: (2018)

Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach
por: Cao, Yang, et al.
Publicado: (2022)

Building Ethereum Dapps: decentralized applications on the Ethereum blockchain
por: Infante, Roberto
Publicado: (2019)

Systems genetics approaches for understanding complex traits with relevance for human disease
por: Allayee, Hooman, et al.
Publicado: (2023)

Quantitative analysis of 3-dimensional facial soft tissue photographic images: technical methods and clinical application
por: Nanda, Vikrum, et al.
Publicado: (2015)

High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping
por: Rau, Christoph D., et al.
Publicado: (2015)

Near-roadway air pollution, immune cells and adipokines among obese young adults
por: Rahman, Md Mostafijur, et al.
Publicado: (2022)

Social Networking of Group Two Innate Lymphoid Cells in Allergy and Asthma
por: Hurrell, Benjamin P., et al.
Publicado: (2018)

Allele-specific expression and eQTL analysis in mouse adipose tissue
por: Hasin-Brumshtein, Yehudit, et al.
Publicado: (2014)

Genetic and Clinical Markers of Elevated Liver Fat Content in Overweight and Obese Hispanic Children
por: Walker, Ryan W., et al.
Publicado: (2013)

Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease
por: Hartiala, Jaana A., et al.
Publicado: (2016)

The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits
por: Lusis, Aldons J., et al.
Publicado: (2016)

Ethereum projects for beginners: build blockchain-based cryptocurrencies, smart contracts, and DApps
por: Vaneetvelde, Kenny
Publicado: (2018)

Building a Secure Biomedical Data Sharing Decentralized App (DApp): Tutorial
por: Johnson, Matthew, et al.
Publicado: (2019)

Suppressive Role of Bam32/DAPP1 in Chemokine-Induced Neutrophil Recruitment
por: Hao, Li, et al.
Publicado: (2021)

Comparative genomics to examine the endophytic potential of Pantoea agglomerans DAPP-PG 734
por: Sulja, Arburon, et al.
Publicado: (2022)

Exposure to Nanoscale Particulate Matter from Gestation to Adulthood Impairs Metabolic Homeostasis in Mice
por: Woodward, Nicholas C., et al.
Publicado: (2019)

Meta-Analysis Identifies Gene-by-Environment Interactions as Demonstrated in a Study of 4,965 Mice
por: Kang, Eun Yong, et al.
Publicado: (2014)

Synergistic interaction between the type III secretion system of the endophytic bacterium Pantoea agglomerans DAPP‐PG 734 and the virulence of the causal agent of olive knot Pseudomonas savastanoi pv. savastanoi DAPP‐PG 722
por: Moretti, Chiaraluce, et al.
Publicado: (2021)

Building Blockchain projects: develop real-time practical DApps using Ethereum and JavaScript
por: Prusty, Narayan
Publicado: (2017)

A Federated Blockchain Architecture for File Storage with Improved Latency and Reliability in IoT DApp Services
por: Na, Dongjun, et al.
Publicado: (2023)

Effect of menopausal hormone therapy on methylation levels in early and late postmenopausal women
por: Hilser, James R., et al.
Publicado: (2022)

Systems Genetic Analysis of Osteoblast-Lineage Cells
por: Calabrese, Gina, et al.
Publicado: (2012)

Correction for Hirose et al., “Impact of a Demyelination-Inducing Central Nervous System Virus on Expression of Demyelination Genes in Type 2 Lymphoid Cells”
por: Hirose, Satoshi, et al.
Publicado: (2021)

Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes
por: Galle-Treger, Lauriane, et al.
Publicado: (2019)

Bam32/DAPP1-Dependent Neutrophil Reactive Oxygen Species in WKYMVm-Induced Microvascular Hyperpermeability
por: Hao, Li, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_56efcvjjqr50mgcoc3vm756fcj