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Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes
Germline genome defense evolves to recognize and suppress retrotransposons. One of defensive mechanisms is the PIWI-associated RNA (piRNA) pathway, which employs small RNAs for sequence-specific repression. The loss of the piRNA pathway in mice causes male sterility while females remain fertile. Unl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944382/ https://www.ncbi.nlm.nih.gov/pubmed/31860668 http://dx.doi.org/10.1371/journal.pgen.1008261 |