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Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes

Germline genome defense evolves to recognize and suppress retrotransposons. One of defensive mechanisms is the PIWI-associated RNA (piRNA) pathway, which employs small RNAs for sequence-specific repression. The loss of the piRNA pathway in mice causes male sterility while females remain fertile. Unl...

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Detalles Bibliográficos
Autores principales:	Taborska, Eliska, Pasulka, Josef, Malik, Radek, Horvat, Filip, Jenickova, Irena, Jelić Matošević, Zoe, Svoboda, Petr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944382/ https://www.ncbi.nlm.nih.gov/pubmed/31860668 http://dx.doi.org/10.1371/journal.pgen.1008261

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