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Benchmarking network algorithms for contextualizing genes of interest

Computational approaches have shown promise in contextualizing genes of interest with known molecular interactions. In this work, we evaluate seventeen previously published algorithms based on characteristics of their output and their performance in three tasks: cross validation, prediction of drug...

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Detalles Bibliográficos
Autores principales: Hill, Abby, Gleim, Scott, Kiefer, Florian, Sigoillot, Frederic, Loureiro, Joseph, Jenkins, Jeremy, Morris, Melody K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944391/
https://www.ncbi.nlm.nih.gov/pubmed/31860671
http://dx.doi.org/10.1371/journal.pcbi.1007403