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Loss of Chondroitin Sulfate Modification Causes Inflammation and Neurodegeneration in skt Mice

One major aspect of the aging process is the onset of chronic, low-grade inflammation that is highly associated with age-related diseases. The molecular mechanisms that regulate these processes have not been fully elucidated. We have identified a spontaneous mutant mouse line, small with kinky tail...

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Detalles Bibliográficos
Autores principales: Macke, Erica L., Henningsen, Erika, Jessen, Erik, Zumwalde, Nicholas A., Landowski, Michael, Western, Daniel E., Lee, Wei-Hua, Liu, Che, Gruenke, Nathan P., Doebley, Anna-Lisa, Miller, Samuel, Pattnaik, Bikash, Ikeda, Sakae, Gumperz, Jenny E., Ikeda, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944401/
https://www.ncbi.nlm.nih.gov/pubmed/31754016
http://dx.doi.org/10.1534/genetics.119.302834