A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life

To become and remain functional, individual neuron types must select during development and maintain throughout life their distinct terminal identity features, such as expression of specific neurotransmitter receptors, ion channels and neuropeptides. Here, we report a molecular mechanism that enable...

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Detalles Bibliográficos
Autores principales: Feng, Weidong, Li, Yinan, Dao, Pauline, Aburas, Jihad, Islam, Priota, Elbaz, Benayahu, Kolarzyk, Anna, Brown, André EX, Kratsios, Paschalis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944445/
https://www.ncbi.nlm.nih.gov/pubmed/31902393
http://dx.doi.org/10.7554/eLife.50065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944445/
https://www.ncbi.nlm.nih.gov/pubmed/31902393
http://dx.doi.org/10.7554/eLife.50065

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