Essential role for InSyn1 in dystroglycan complex integrity and cognitive behaviors in mice

Human mutations in the dystroglycan complex (DGC) result in not only muscular dystrophy but also cognitive impairments. However, the molecular architecture critical for the synaptic organization of the DGC in neurons remains elusive. Here, we report Inhibitory Synaptic protein 1 (InSyn1) is a critic...

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Detalles Bibliográficos
Autores principales: Uezu, Akiyoshi, Hisey, Erin, Kobayashi, Yoshihiko, Gao, Yudong, Bradshaw, Tyler WA, Devlin, Patrick, Rodriguiz, Ramona, Tata, Purushothama Rao, Soderling, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944460/
https://www.ncbi.nlm.nih.gov/pubmed/31829939
http://dx.doi.org/10.7554/eLife.50712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944460/
https://www.ncbi.nlm.nih.gov/pubmed/31829939
http://dx.doi.org/10.7554/eLife.50712

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