THAP11(F80L) cobalamin disorder-associated mutation reveals normal and pathogenic THAP11 functions in gene expression and cell proliferation

Twelve human THAP proteins share the THAP domain, an evolutionary conserved zinc-finger DNA-binding domain. Studies of different THAP proteins have indicated roles in gene transcription, cell proliferation and development. We have analyzed this protein family, focusing on THAP7 and THAP11. We show t...

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Detalles Bibliográficos
Autores principales: Dehaene, Harmonie, Praz, Viviane, Lhôte, Philippe, Lopes, Maykel, Herr, Winship
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944463/
https://www.ncbi.nlm.nih.gov/pubmed/31905202
http://dx.doi.org/10.1371/journal.pone.0224646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944463/
https://www.ncbi.nlm.nih.gov/pubmed/31905202
http://dx.doi.org/10.1371/journal.pone.0224646

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