CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth

Pancreatic ductal adenocarcinoma (PDAC) shows great cellular heterogeneity, with pronounced epithelial and mesenchymal cancer cell populations. However, the cellular hierarchy underlying PDAC cell diversity is unknown. Here we identify the tetraspanin CD9 as a marker of PDAC tumour-initiating cells....

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Detalles Bibliográficos
Autores principales: Wang, Victoria M.-Y., Ferreira, Rute M. M., Almagro, Jorge, Evan, Theodore, Legrave, Nathalie, Zaw Thin, May, Frith, David, Carvalho, Joana, Barry, David J., Snijders, Ambrosius P., Herbert, Eleanor, Nye, Emma L., MacRae, James I., Behrens, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944508/
https://www.ncbi.nlm.nih.gov/pubmed/31685994
http://dx.doi.org/10.1038/s41556-019-0407-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944508/
https://www.ncbi.nlm.nih.gov/pubmed/31685994
http://dx.doi.org/10.1038/s41556-019-0407-1

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