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Lipid lowering and Alzheimer disease risk: A mendelian randomization study

OBJECTIVE: To examine whether genetic variation affecting the expression or function of lipid‐lowering drug targets is associated with Alzheimer disease (AD) risk, to evaluate the potential impact of long‐term exposure to corresponding therapeutics. METHODS: We conducted Mendelian randomization anal...

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Detalles Bibliográficos
Autores principales: Williams, Dylan M., Finan, Chris, Schmidt, Amand F., Burgess, Stephen, Hingorani, Aroon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944510/
https://www.ncbi.nlm.nih.gov/pubmed/31714636
http://dx.doi.org/10.1002/ana.25642