Cargando…

Intracellular XBP1-IL-24 axis dismantles cytotoxic unfolded protein response in the liver

Endoplasmic reticulum (ER) stress-associated cell death is prevalent in various liver diseases. However, the determinant mechanism how hepatocytes survive unresolved stress was still unclear. Interleukin-24 (IL-24) was previously found to promote ER stress-mediated cell death, and yet its expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jianye, Hu, Bian, Zhao, Zhicong, Zhang, Haiyan, Zhang, He, Zhao, Zhenjun, Ma, Xiong, Shen, Bin, Sun, Beicheng, Huang, Xingxu, Hou, Jiajie, Xia, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944701/
https://www.ncbi.nlm.nih.gov/pubmed/31907348
http://dx.doi.org/10.1038/s41419-019-2209-6