BCL-XL expression is essential for human erythropoiesis and engraftment of hematopoietic stem cells

The anti-apoptotic BCL-2 proteins (BCL-2, BCL-XL, MCL-1, A1, BCL-W) counteract apoptotic signals emerging during development and under stress conditions, and are thus essential for the survival of every cell. While the “BCL-2 addiction” of different cell types is well described in mouse models, ther...

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Detalles Bibliográficos
Autores principales: Afreen, Sehar, Bohler, Sheila, Müller, Alexandra, Demmerath, Eva-Maria, Weiss, Julia Miriam, Jutzi, Jonas Samuel, Schachtrup, Kristina, Kunze, Mirjam, Erlacher, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944703/
https://www.ncbi.nlm.nih.gov/pubmed/31907357
http://dx.doi.org/10.1038/s41419-019-2203-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944703/
https://www.ncbi.nlm.nih.gov/pubmed/31907357
http://dx.doi.org/10.1038/s41419-019-2203-z

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