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Tacrolimus‐induced hypomagnesemia and hypercalciuria requires FKBP12 suggesting a role for calcineurin

Calcineurin inhibitors (CNIs) are immunosuppressive drugs used to prevent graft rejection after organ transplant. Common side effects include renal magnesium wasting and hypomagnesemia, which may contribute to new‐onset diabetes mellitus, and hypercalciuria, which may contribute to post‐transplant o...

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Detalles Bibliográficos
Autores principales: Gratreak, Brittany D. K., Swanson, Elizabeth A., Lazelle, Rebecca A., Jelen, Sabina K., Hoenderop, Joost, Bindels, René J., Yang, Chao‐Ling, Ellison, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944708/
https://www.ncbi.nlm.nih.gov/pubmed/31908154
http://dx.doi.org/10.14814/phy2.14316