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In vitro and in silico insights into tyrosinase inhibitors with (E)-benzylidene-1-indanone derivatives
Tyrosinase is a key enzyme responsible for melanin biosynthesis and is effective in protecting skin damage caused by ultraviolet radiation. As part of ongoing efforts to discover potent tyrosinase inhibitors, we systematically designed and synthesized thirteen (E)-benzylidene-1-indanone derivatives...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944710/ https://www.ncbi.nlm.nih.gov/pubmed/31921392 http://dx.doi.org/10.1016/j.csbj.2019.07.017 |