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In vitro and in silico insights into tyrosinase inhibitors with (E)-benzylidene-1-indanone derivatives

Tyrosinase is a key enzyme responsible for melanin biosynthesis and is effective in protecting skin damage caused by ultraviolet radiation. As part of ongoing efforts to discover potent tyrosinase inhibitors, we systematically designed and synthesized thirteen (E)-benzylidene-1-indanone derivatives...

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Detalles Bibliográficos
Autores principales: Jung, Hee Jin, Noh, Sang Gyun, Park, Yujin, Kang, Dongwan, Chun, Pusoon, Chung, Hae Young, Moon, Hyung Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944710/
https://www.ncbi.nlm.nih.gov/pubmed/31921392
http://dx.doi.org/10.1016/j.csbj.2019.07.017

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