NGP 555, a γ-secretase modulator, shows a beneficial shift in the ratio of amyloid biomarkers in human cerebrospinal fluid at safe doses

INTRODUCTION: Currently, there is no cure for Alzheimer's disease (AD), and it is widely accepted that AD is a complex disease with multiple approaches necessary to prevent and treat the disease. METHODS: Using amyloid biomarkers in human cerebrospinal fluid, pharmacokinetic, safety, and metabo...

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Detalles Bibliográficos
Autores principales: Kounnas, Maria Z., Durakoglugil, Murat S., Herz, Joachim, Comer, William T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944734/
https://www.ncbi.nlm.nih.gov/pubmed/31921961
http://dx.doi.org/10.1016/j.trci.2019.06.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944734/
https://www.ncbi.nlm.nih.gov/pubmed/31921961
http://dx.doi.org/10.1016/j.trci.2019.06.006

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