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A genetic signature including apolipoprotein Eε4 potentiates the risk of herpes simplex–associated Alzheimer's disease

INTRODUCTION: Herpes simplex virus type 1 (HSV1) in combination with genetic susceptibility has previously been implicated in Alzheimer's disease (AD) pathogenesis. METHODS: Plasma from 360 AD cases, obtained on average 9.6 years before diagnosis, and their age- and sex-matched controls, were a...

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Detalles Bibliográficos
Autores principales: Lopatko Lindman, Karin, Weidung, Bodil, Olsson, Jan, Josefsson, Maria, Kok, Eloise, Johansson, Anders, Eriksson, Sture, Hallmans, Göran, Elgh, Fredrik, Lövheim, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944738/
https://www.ncbi.nlm.nih.gov/pubmed/31921962
http://dx.doi.org/10.1016/j.trci.2019.09.014