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Heparan Sulfate Structure Affects Autophagy, Lifespan, Responses to Oxidative Stress, and Cell Degeneration in Drosophila parkin Mutants
Autophagy is a catabolic process that provides cells with energy and molecular building blocks during nutritional stress. Autophagy also removes misfolded proteins and damaged organelles, a critical mechanism for cellular repair. Earlier work demonstrated that heparan sulfate proteoglycans, an abund...
Autores principales: | Reynolds-Peterson, Claire, Xu, Jie, Zhao, Na, Cruse, Casey, Yonel, Brandon, Trasorras, Claire, Toyoda, Hidenao, Kinoshita-Toyoda, Akiko, Dobson, Jennifer, Schultheis, Nicholas, Jiang, Mei, Selleck, Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945019/ https://www.ncbi.nlm.nih.gov/pubmed/31672849 http://dx.doi.org/10.1534/g3.119.400730 |
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