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Heparan Sulfate Structure Affects Autophagy, Lifespan, Responses to Oxidative Stress, and Cell Degeneration in Drosophila parkin Mutants

Autophagy is a catabolic process that provides cells with energy and molecular building blocks during nutritional stress. Autophagy also removes misfolded proteins and damaged organelles, a critical mechanism for cellular repair. Earlier work demonstrated that heparan sulfate proteoglycans, an abund...

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Detalles Bibliográficos
Autores principales: Reynolds-Peterson, Claire, Xu, Jie, Zhao, Na, Cruse, Casey, Yonel, Brandon, Trasorras, Claire, Toyoda, Hidenao, Kinoshita-Toyoda, Akiko, Dobson, Jennifer, Schultheis, Nicholas, Jiang, Mei, Selleck, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945019/
https://www.ncbi.nlm.nih.gov/pubmed/31672849
http://dx.doi.org/10.1534/g3.119.400730