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A Functional Analysis of the Drosophila Gene hindsight: Evidence for Positive Regulation of EGFR Signaling

We have investigated the relationship between the function of the gene hindsight (hnt), which is the Drosophila homolog of Ras Responsive Element Binding protein-1 (RREB-1), and the EGFR signaling pathway. We report that hnt mutant embryos are defective in EGFR signaling dependent processes, namely...

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Detalles Bibliográficos
Autores principales: Kim, Minhee, Du, Olivia Y., Whitney, Rachael J., Wilk, Ronit, Hu, Jack, Krause, Henry M., Kavaler, Joshua, Reed, Bruce H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945037/
https://www.ncbi.nlm.nih.gov/pubmed/31649045
http://dx.doi.org/10.1534/g3.119.400829