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TBK1‐mediated phosphorylation of LC3C and GABARAP‐L2 controls autophagosome shedding by ATG4 protease

Autophagy is a highly conserved catabolic process through which defective or otherwise harmful cellular components are targeted for degradation via the lysosomal route. Regulatory pathways, involving post‐translational modifications such as phosphorylation, play a critical role in controlling this t...

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Detalles Bibliográficos
Autores principales: Herhaus, Lina, Bhaskara, Ramachandra M, Lystad, Alf Håkon, Gestal‐Mato, Uxía, Covarrubias‐Pinto, Adriana, Bonn, Florian, Simonsen, Anne, Hummer, Gerhard, Dikic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945063/
https://www.ncbi.nlm.nih.gov/pubmed/31709703
http://dx.doi.org/10.15252/embr.201948317