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TBK1‐mediated phosphorylation of LC3C and GABARAP‐L2 controls autophagosome shedding by ATG4 protease
Autophagy is a highly conserved catabolic process through which defective or otherwise harmful cellular components are targeted for degradation via the lysosomal route. Regulatory pathways, involving post‐translational modifications such as phosphorylation, play a critical role in controlling this t...
Autores principales: | Herhaus, Lina, Bhaskara, Ramachandra M, Lystad, Alf Håkon, Gestal‐Mato, Uxía, Covarrubias‐Pinto, Adriana, Bonn, Florian, Simonsen, Anne, Hummer, Gerhard, Dikic, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945063/ https://www.ncbi.nlm.nih.gov/pubmed/31709703 http://dx.doi.org/10.15252/embr.201948317 |
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