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A Refined Open State of the Glycine Receptor Obtained via Molecular Dynamics Simulations
Pentameric ligand-gated ion channels are key players in mediating fast neurotransmission. Glycine receptors are chloride-selective members of this receptor family that mediate inhibitory synaptic transmission and are implicated in neurological disorders including autism and hyperekplexia. They have...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945115/ https://www.ncbi.nlm.nih.gov/pubmed/31753620 http://dx.doi.org/10.1016/j.str.2019.10.019 |