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Alterations of Mitochondria and Related Metabolic Pathways in Leukemia: A Narrative Review

Dysregulation of mitochondrial function often precedes malignant transformation of hematopoietic stem cells (HSCs). Mitochondria have a direct role in the maintenance of HSC functions. For example, D-2-hydroxyglutarate, generated due to the activity of mutated mitochondrial isocitrate dehydrogenase...

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Detalles Bibliográficos
Autor principal: Al Ageeli, Essam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945320/
https://www.ncbi.nlm.nih.gov/pubmed/31929772
http://dx.doi.org/10.4103/sjmms.sjmms_112_18