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Alterations of Mitochondria and Related Metabolic Pathways in Leukemia: A Narrative Review
Dysregulation of mitochondrial function often precedes malignant transformation of hematopoietic stem cells (HSCs). Mitochondria have a direct role in the maintenance of HSC functions. For example, D-2-hydroxyglutarate, generated due to the activity of mutated mitochondrial isocitrate dehydrogenase...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Wolters Kluwer - Medknow
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945320/ https://www.ncbi.nlm.nih.gov/pubmed/31929772 http://dx.doi.org/10.4103/sjmms.sjmms_112_18 |