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Structural basis of polyethylene glycol recognition by antibody

BACKGROUND: Polyethylene glycol (PEG) is widely used in industry and medicine. Anti-PEG antibodies have been developed for characterizing PEGylated drugs and other applications. However, the underlying mechanism for specific PEG binding has not been elucidated. METHODS: The Fab of two cognate anti-P...

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Detalles Bibliográficos
Autores principales: Lee, Cheng-Chung, Su, Yu-Cheng, Ko, Tzu-Ping, Lin, Li-Ling, Yang, Chih-Ya, Chang, Stanley Shi-Chung, Roffler, Steve R., Wang, Andrew H.-J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945545/
https://www.ncbi.nlm.nih.gov/pubmed/31907057
http://dx.doi.org/10.1186/s12929-019-0589-7