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Malignant transformation of oral leukoplakia is associated with macrophage polarization

BACKGROUND: Most oral squamous cell carcinomas (OSCC) occur on the basis of oral leukoplakias (OLP). The histologic degree of dysplasia is insufficient for the prediction of OLP malignant transformation. Immunologic parameters are gaining importance for prognostic assessment and therapy of cancer. M...

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Detalles Bibliográficos
Autores principales: Weber, Manuel, Wehrhan, Falk, Baran, Christoph, Agaimy, Abbas, Büttner-Herold, Maike, Öztürk, Hatice, Neubauer, Kristina, Wickenhauser, Claudia, Kesting, Marco, Ries, Jutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945578/
https://www.ncbi.nlm.nih.gov/pubmed/31910881
http://dx.doi.org/10.1186/s12967-019-02191-0