The effects of oral administration of Cola nitida on the pharmacokinetic profile of metoclopramide in rabbits

BACKGROUND: Cola nitida is commonly chewed in many West African cultures to ease hunger pangs and sometimes for their stimulant and euphoriant qualities. Metoclopramide is a known substrate for P-gp, SULT2A1 and CYP2D6 and studies have revealed that caffeine- a major component of Cola nitida can ind...

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Detalles Bibliográficos
Autores principales: Amadi, Cecilia Nwadiuto, Nwachukwu, Wisdom Izuchukwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945619/
https://www.ncbi.nlm.nih.gov/pubmed/31907041
http://dx.doi.org/10.1186/s40360-019-0379-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945619/
https://www.ncbi.nlm.nih.gov/pubmed/31907041
http://dx.doi.org/10.1186/s40360-019-0379-6

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