Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells

Constitutive activation of the canonical NF-κB pathway has been associated with a variety of human pathologies. However, molecular mechanisms through which canonical NF-κB affects hematopoiesis remain elusive. Here, we demonstrate that deregulated canonical NF-κB signals in hematopoietic stem cells...

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Detalles Bibliográficos
Autores principales: Nakagawa, Masahiro Marshall, Rathinam, Chozha Vendan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945759/
https://www.ncbi.nlm.nih.gov/pubmed/30463008
http://dx.doi.org/10.1016/j.celrep.2018.10.071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945759/
https://www.ncbi.nlm.nih.gov/pubmed/30463008
http://dx.doi.org/10.1016/j.celrep.2018.10.071

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