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Downregulation of SRPK2 promotes cell cycle arrest through E2F1 in non-small cell lung cancer

Serine-arginine protein kinase (SRPK) belongs to a class of cell cycle regulating kinases that can phosphorylate proteins containing serine/arginine-Rich (SR) regions. SR proteins are a family of RNAbinding phosphoproteins that control both constitutive and alternative pre-mRNA splicing events. Howe...

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Detalles Bibliográficos
Autores principales: Li, Xin, Yang, Shaoyu, Zhang, Minna, Xie, Shuhuan, Xie, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945924/
https://www.ncbi.nlm.nih.gov/pubmed/31833327
http://dx.doi.org/10.4081/ejh.2019.3067