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Nuclear Factor-κB Increases Intracellular Calcium by Upregulation of Na(+)-Ca(2+) Exchanger 1 in Cerulein-Induced Acute Pancreatitis

OBJECTIVES: The mechanisms underlying pathogenesis of acute pancreatitis (AP) are still not completely understood. An early, critical feature of AP is aberrant calcium (Ca(2+)) signaling, termed Ca(2+) overload, within pancreatic acinar cells. This study aimed to develop a model system in rats for A...

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Detalles Bibliográficos
Autores principales: Chen, Yuyang, Li, Wanling, Xie, Rui, Tang, Bo, Xiao, YuFeng, Yang, Feng, Chen, Siyuan, Yu, Senyuan, Yang, Shiming, Dong, Hui, Guo, Hong, Liu, Jing-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946105/
https://www.ncbi.nlm.nih.gov/pubmed/31856086
http://dx.doi.org/10.1097/MPA.0000000000001465