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EF-hand like Region in the N-terminus of Anoctamin 1 Modulates Channel Activity by Ca(2+) and Voltage
Anoctamin1 (ANO1) also known as TMEM16A is a transmembrane protein that functions as a Ca(2+) activated chloride channel. Recently, the structure determination of a fungal Nectria haematococca TMEM16 (nhTMEM16) scramblase by X-ray crystallography and a mouse ANO1 by cryo-electron microscopy has prov...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Brain and Neural Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946113/ https://www.ncbi.nlm.nih.gov/pubmed/31902154 http://dx.doi.org/10.5607/en.2019.28.6.658 |