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EF-hand like Region in the N-terminus of Anoctamin 1 Modulates Channel Activity by Ca(2+) and Voltage

Anoctamin1 (ANO1) also known as TMEM16A is a transmembrane protein that functions as a Ca(2+) activated chloride channel. Recently, the structure determination of a fungal Nectria haematococca TMEM16 (nhTMEM16) scramblase by X-ray crystallography and a mouse ANO1 by cryo-electron microscopy has prov...

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Detalles Bibliográficos
Autores principales:	Tak, Min Ho, Jang, Yongwoo, Son, Woo Sung, Yang, Young Duk, Oh, Uhtaek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Brain and Neural Sciences 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946113/ https://www.ncbi.nlm.nih.gov/pubmed/31902154 http://dx.doi.org/10.5607/en.2019.28.6.658

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