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The virulence domain of Shigella IcsA contains a subregion with specific host cell adhesion function

Shigella species cause bacillary dysentery, especially among young individuals. Shigellae target the human colon for invasion; however, the initial adhesion mechanism is poorly understood. The Shigella surface protein IcsA, in addition to its role in actin-based motility, acts as a host cell adhesin...

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Detalles Bibliográficos
Autores principales: Qin, Jilong, Doyle, Matthew Thomas, Tran, Elizabeth Ngoc Hoa, Morona, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946128/
https://www.ncbi.nlm.nih.gov/pubmed/31910229
http://dx.doi.org/10.1371/journal.pone.0227425