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Bidirectional Optogenetically-Induced Plasticity of Evoked Responses in the Rat Medial Prefrontal Cortex Can Impair or Enhance Cognitive Set-Shifting

Chronic stress compromises cognition, including executive function mediated in the medial prefrontal cortex (mPFC). To investigate mechanisms underlying these processes, we use chronic unpredictable stress (CUS), which reduces activity in the mPFC and impairs cognitive set-shifting, a measure of cog...

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Detalles Bibliográficos
Autores principales: Bulin, Sarah E., Hohl, Kelly M., Paredes, Denisse, Silva, Jeri D., Morilak, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946542/
https://www.ncbi.nlm.nih.gov/pubmed/31852759
http://dx.doi.org/10.1523/ENEURO.0363-19.2019