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Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution

Biological tissues exhibit complex spatial heterogeneity that directs the functions of multicellular organisms. Quantifying protein expression is essential for elucidating processes within complex biological assemblies. Imaging mass spectrometry (IMS) is a powerful emerging tool for mapping the spat...

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Detalles Bibliográficos
Autores principales: Piehowski, Paul D., Zhu, Ying, Bramer, Lisa M., Stratton, Kelly G., Zhao, Rui, Orton, Daniel J., Moore, Ronald J., Yuan, Jia, Mitchell, Hugh D., Gao, Yuqian, Webb-Robertson, Bobbie-Jo M., Dey, Sudhansu K., Kelly, Ryan T., Burnum-Johnson, Kristin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946663/
https://www.ncbi.nlm.nih.gov/pubmed/31911630
http://dx.doi.org/10.1038/s41467-019-13858-z