Cargando…

Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes

Mutation-specific effects of cancer driver genes influence drug responses and the success of clinical trials. We reasoned that these effects could unbalance the distribution of each mutation across different cancer types, as a result, the cancer preference can be used to distinguish the effects of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Xiaobao, Huang, Dandan, Yi, Xianfu, Zhang, Shijie, Wang, Zhao, Yan, Bin, Chung Sham, Pak, Chen, Kexin, Jun Li, Mulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946677/
https://www.ncbi.nlm.nih.gov/pubmed/31925297
http://dx.doi.org/10.1038/s42003-019-0736-4