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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes
Mutation-specific effects of cancer driver genes influence drug responses and the success of clinical trials. We reasoned that these effects could unbalance the distribution of each mutation across different cancer types, as a result, the cancer preference can be used to distinguish the effects of t...
Autores principales: | Dong, Xiaobao, Huang, Dandan, Yi, Xianfu, Zhang, Shijie, Wang, Zhao, Yan, Bin, Chung Sham, Pak, Chen, Kexin, Jun Li, Mulin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946677/ https://www.ncbi.nlm.nih.gov/pubmed/31925297 http://dx.doi.org/10.1038/s42003-019-0736-4 |
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