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Deep-Channel uses deep neural networks to detect single-molecule events from patch-clamp data

Single-molecule research techniques such as patch-clamp electrophysiology deliver unique biological insight by capturing the movement of individual proteins in real time, unobscured by whole-cell ensemble averaging. The critical first step in analysis is event detection, so called “idealisation”, wh...

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Detalles Bibliográficos
Autores principales: Celik, Numan, O’Brien, Fiona, Brennan, Sean, Rainbow, Richard D., Dart, Caroline, Zheng, Yalin, Coenen, Frans, Barrett-Jolley, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946689/
https://www.ncbi.nlm.nih.gov/pubmed/31925311
http://dx.doi.org/10.1038/s42003-019-0729-3