Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization

Modern high-throughput experiments provide a rich resource to investigate causal determinants of disease risk. Mendelian randomization (MR) is the use of genetic variants as instrumental variables to infer the causal effect of a specific risk factor on an outcome. Multivariable MR is an extension of...

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Detalles Bibliográficos
Autores principales: Zuber, Verena, Colijn, Johanna Maria, Klaver, Caroline, Burgess, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946691/
https://www.ncbi.nlm.nih.gov/pubmed/31911605
http://dx.doi.org/10.1038/s41467-019-13870-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946691/
https://www.ncbi.nlm.nih.gov/pubmed/31911605
http://dx.doi.org/10.1038/s41467-019-13870-3

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