Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

Impaired lung function is often caused by cigarette smoking, making it challenging to disentangle its role in lung cancer susceptibility. Investigation of the shared genetic basis of these phenotypes in the UK Biobank and International Lung Cancer Consortium (29,266 cases, 56,450 controls) shows tha...

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Detalles Bibliográficos
Autores principales: Kachuri, Linda, Johansson, Mattias, Rashkin, Sara R., Graff, Rebecca E., Bossé, Yohan, Manem, Venkata, Caporaso, Neil E., Landi, Maria Teresa, Christiani, David C., Vineis, Paolo, Liu, Geoffrey, Scelo, Ghislaine, Zaridze, David, Shete, Sanjay S., Albanes, Demetrius, Aldrich, Melinda C., Tardón, Adonina, Rennert, Gad, Chen, Chu, Goodman, Gary E., Doherty, Jennifer A., Bickeböller, Heike, Field, John K., Davies, Michael P., Dawn Teare, M., Kiemeney, Lambertus A., Bojesen, Stig E., Haugen, Aage, Zienolddiny, Shanbeh, Lam, Stephen, Le Marchand, Loïc, Cheng, Iona, Schabath, Matthew B., Duell, Eric J., Andrew, Angeline S., Manjer, Jonas, Lazarus, Philip, Arnold, Susanne, McKay, James D., Emami, Nima C., Warkentin, Matthew T., Brhane, Yonathan, Obeidat, Ma’en, Martin, Richard M., Relton, Caroline, Davey Smith, George, Haycock, Philip C., Amos, Christopher I., Brennan, Paul, Witte, John S., Hung, Rayjean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946810/
https://www.ncbi.nlm.nih.gov/pubmed/31911640
http://dx.doi.org/10.1038/s41467-019-13855-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946810/
https://www.ncbi.nlm.nih.gov/pubmed/31911640
http://dx.doi.org/10.1038/s41467-019-13855-2

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