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Impact of pre‐therapy glioblastoma multiforme microenvironment on clinical response to autologous CMV‐specific T‐cell therapy

OBJECTIVES: Clinical response to antibody‐based immunotherapies targeting checkpoint inhibitors is critically dependent on the tumor immune microenvironment (TIME). However, the precise impact of the TIME on adoptive cellular immunotherapy remains unexplored. Here we have conducted a long‐term follo...

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Detalles Bibliográficos
Autores principales: Walker, David G, Shakya, Reshma, Morrison, Beth, Neller, Michelle A, Matthews, Katherine K, Nicholls, John, Smith, Corey, Khanna, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946915/
https://www.ncbi.nlm.nih.gov/pubmed/31929892
http://dx.doi.org/10.1002/cti2.1088